3β-HSD	3β hydroxysteroid dehydrogenase
4E-BP1	Eukaryotic translation initiation factor 4E binding protein 1
ADT	Androgen deprivation therapy
AD	Androstenedione
AGC	cAMP-dependent, cGMP-dependent and protein kinase C
AKTi	AKT inhibitor
AMP	Adenosine monophosphate
AMPK	5′ AMP-activated protein kinase
APC	Adenomatous polyposis coli
AR	Androgen receptor
ARE	Androgen responsive element
ARF1	Adenosine ribosylation factor 1
ATG14	Autophagy related 14 homolog
ATP	Adenosine triphosphate
AXIN	Axis inhibitor protein
BAD	Bcl-2-associated death promoter
BMK-1	Big mitogen-activated protein kinase-1
CaMKII	Calmodulin-dependent kinase 2
CAMKKβ	Ca(2+)/calmodulin-dependent protein kinase kinase β
CAV1	Caveolin-1
CDK4	Cyclin-dependent kinase 4
c-JUN	Transcription factor AP-1
CK1	Casein kinase 1
CAN	Copy number alteration
CREB	cAMP response element-binding protein
CRPC	Castrate resistant prostate cancer
CYP17A1	Cytochrome P450 17A1
DEPTOR	Dishevelled, EGL-10 and pleckstrin (DEP) domain-containing mTOR-interacting protein
DFCI	Dana-Farber Cancer Institute
DHEA	Dehydroepiandrosterone
DHTDVL	DihydrotestosteroneDisheveled
EIF4E	Eukaryotic translation initiation factor 4E
EGF	Epidermal growth factor
EGFR	Epidermal growth factor receptor
EGR1	Early growth response 1
EMT	Epithelial-to-mesenchymal transition
ERG1	ETS-related Gene 1
ERK1	Mitogen-activated protein kinase 3
ERK2	Mitogen-activated protein kinase 1
EZH2	Enhancer of zeste homolog 2
FKBP5	FK506 binding protein 5
FOXO	Forkhead box protein O
FGFR	Fibroblast growth factor receptor
FZD	Frizzled family receptor
GAB1	GRB2-associated binder-1
GDP	Guanosine diphosphate
GLUT3	Glucose transporter 3
GnRH	Gonadotrophin-releasing hormone
GPCR	G-protein coupled receptor
GR	Glucocorticoid receptor
GRB2	Growth factor receptor-bound protein 2
GRB10	Growth factor binding protein 10
GSK3β	Glycogen synthase kinase 3 beta
GTP	Guanosine triphosphate
HDAC3	Histone deacetylase 3
HER2/3	Human epidermal growth factor receptor 2/3
HSD3B/17B3	Hydroxysteroid dehydrogenase 3B/17B3
HSP70/90	Heat shock protein 70/90
IGF	Insulin growth factor
IGF-1	Insulin growth factor 1
IHC	Immunohistochemistry
IL6	Interleukin 6
INPP4B	Inositol polyphosphate 4-phosphatase type II
INPP5D	Inositol polyphosphate-5-phosphatase D
INPP5J	Inositol polyphosphate-5-phosphatase J
INPPL1	Inositol polyphosphate phosphatase like 1
IRS	Insulin receptor substrate
IRS1	Insulin receptor substrate protein 1
KLK3	Kallikrein related peptidase 3
LAT1/2/3	L-type amino acid transporter 1/2/3
LDHA	L-lactate dehydrogenase A chain
LEF	Lymphoid enhancer binding factor
LH	Luteinizing hormone
LHRH	Luteinizing hormone-releasing hormone
LKB1	Liver kinase B1
LRP5/6	Low-density lipoprotein receptor-related proteins 5 and 6
MAPK	Mitogen-activated protein kinase
MAP3K7	Mitogen-activated protein kinase kinase kinase 7
mCRPC	Metastatic castrate resistant prostate cancer
MDM2	Mouse double minute 2 homolog
MEK	Mitogen-activated protein kinase kinase
MSKCC	Memorial Sloan Kettering Cancer Centre
mLST8	MTOR associated protein LST8 homolog
MMTV-PyMT	Mouse mammary tumor virus-polyoma middle tumor-antigen
MNK1	MAP kinase interacting serine/threonine kinase 1
MNK2	MAP kinase interacting serine/threonine kinase 2
mSIN1	Mitogen-activated protein kinase associated protein 1 (MAPKAP1)
mTOR	Mammalian target of rapamycin
mTORC1	Mammalian target of rapamycin complex 1
mTORC1i	mTORC1 inhibitor
mTORC2	Mammalian target of rapamycin complex 2
MuSK	Muscle specific kinase
NF-κB	Nuclear factor kappa light chain enhancer of activated B cells
NKX3.1	NK3 Homeobox 1
NSCLC	Non-small-cell lung carcinoma
P	Phosphorylation event
PDK1	Phosphoinositide-dependent kinase 1
PGC-1α	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
PHLPP	PH domain leucine-rich repeat protein phosphatase
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1
PHLPP2	PH domain and leucine rich repeat protein phosphatase 2
PI	Phosphatidylinositol
PI3K	Phosphoinositide 3-kinase
PI(3)P	Phosphatidylinositol 3-phosphate
PI(3,4)P2	Phosphatidylinositol 3,4-bisphosphate
PIN	Prostate intra-epithelial neoplasia
PIP2	Phosphatidylinositol 4,5-bisphosphate
PIP3	Phosphatidylinositol 3,4,5-trisphosphate
PIPP	Proline-rich inositol polyphosphate 5-phosphatase
PKB	Protein kinase B, AKT
PKC	Protein kinase
PKCα	Protein kinase C alpha
PLC	Phospholipase C
PP2A	Protein phosphatase 2A
PPP2CA	Protein phosphatase 2 catalytic subunit Alpha
PRAS40	Proline-rich AKT substrate of 40 kDa
PROTOR1	Protein observed with Rictor-1
PROTOR2	Protein observed with Rictor-2
PSA	Prostate specific antigen
PTEN	Phosphatase and tensin homologue deleted on chromosome 10
PTK7	Protein tyrosine kinase 7
RAF	Rapidly accelerated fibrosarcoma
RAG	Recombination activating genes
RAPTOR	Regulatory-associated protein of mTOR
RBD	Ras-binding domain
RHEB	Ras homolog enriched in brain
RICTOR	Rapamycin-insensitive companion of mTOR
ROR1/2	Receptor tyrosine kinase–like orphan receptor-1 and -2
RPS6	Ribosomal protein S6
rPFS	Radiographic progression-free survival
RSK	90 kDa Ribosomal S6 kinase
RTK	Tyrosine kinase receptor
RYK	Receptor-like tyrosine kinase
S6K	Ribosomal protein S6 kinase/p70 ribosomal S6 kinase
SESN1	Sestrin 1
SGK1	Serum and glucocorticoid regulated kinase 1
SGK2	Serum and glucocorticoid regulated kinase 2
SGK3	Serum and glucocorticoid regulated kinase 3
SH2	Src homology 2
SHIP1	SH2 domain-containing inositol 5′-phosphatase 1
SHIP2	SH2 domain-containing inositol 5′-Phosphatase 2
SLC2A3	Solute carrier family 2, facilitated glucose transporter member 3
SLC43A1	Solute carrier family 43 member 1
SOS	Son of Sevenless
SPOP	Speckle type BTB/POZ protein
SRC-3	Steroid receptor co-activator 3
SRF	Serum response factor
SU2C-PCF IDT	Stand Up To Cancer & Prostate Cancer Foundation International Dream Team
T	Testosterone
TAK1	TGFβ-activated kinase 1
TAZ	Transcriptional coactivator with PDZ binding motif
TBC1D7	TBC1 Domain Family Member 7
TCF	T cell Factor
TCGA	The Cancer Genome Atlas
TEAD	Transcriptional enhanced associate domain
TEL2	Telomere length regulation protein
TGF	Transforming growth factor
TMPRSS2-ERG	Transmembrane protease, serine 2: ETS Transcription Factor fusion
TRAMP	Transgenic adenocarcinoma mouse prostate
TSC1	Tuberous Sclerosis complex 1
TSC2	Tuberous Sclerosis complex 2
TTI1	TELO2 interacting protein 1
Ub	Ubiquitination event
ULK1	Unc-51 Like Autophagy Activating Kinase 1
UVRAG	UV radiation resistance-associated gene; v-ATPase, Vacuolar (H+)-ATPase
VPS15	Vacuolar protein sorting 15
V-ATPase	Vacuolar H+-ATPase
WNT	WNT ligand
YAP	Yes-associated protein