Figure 3.

(A) Correlations among psychiatric scales for depression (BDI), anxiety (GAD7), and sleep (PSQI), and logistic regression for seizure worsening in PwE. Illustrates the relationship among psychometric (PSQI, GAD, BDI) tests in people with epilepsy; subjects that underwent worsening (WPwE) are color-coded (red). In the 3D plot, it can be noted that WPwE tend to fall within a widespread cluster of subjects with more impairment, while there is a dense cluster of subjects with normal tests that do not report worsening. (B) In order to evaluate which psychometric test and variable did independently influence the likelihood of worsening, we designed a logistic regression model that identified the number of ASMs and the PSQI score as significant predictors. We show the increase in the likelihood of worsening for each score of PSQI and for each number of ASMs. WPwE, Worsened People with Epilepsy; nWPwE, non-Worsened People with Epilepsy; ASM, Anti-Seizure Medications; GAD, Generalized Anxiety Disorder 7; PSQI, Pittsburgh Sleep Quality Index; BDI, Beck Depression Inventory.