Table 3.
Alpha- and beta-diversity of gut microbiome in psoriasis compared with healthy controls.
| Study | Indices of α-Diversity |
Gut Microbiota α-Diversity in Psoriasis |
Indices of β-Diversity |
Gut Microbiota β-Diversity in Psoriasis |
|---|---|---|---|---|
| Yeh et al. [19] | Shannon index, Simpson index | No differences were observed | UniFrac analysis (weighted and unweighted analyses), Bray Curtis index |
Significant difference |
| Shapiro et al. [20] | Shannon index, rarefaction curves | No differences were observed | UniFrac analysis (weighted and unweighted analyses) | Significant difference |
| Huang et al. [21] | Shannon index, Simpson index, ACE index, Chao1 index |
Shannon and Simpson indexes—no differences ACE and Chao indexes—decreased in psoriasis |
PCA based on the Bray-Curtis dissimilarity distance | Significant difference |
| Hidalgo-Cantabrana et al. [22] | Shannon index, Chao1 index, Faith’s phylogenetic diversity index |
Lower diversity in psoriasis | unweighted Unifrac analysis | Significant difference |
| Chen et al. [23] | Shannon index, Simpson index, Chao1 index, number of observed OTUs |
No differences were observed | UniFrac analysis (weighted and unweighted analyses), Bray Curtis index |
Significant difference (psoriasis patients with BMI < 25) |
| Codoner et al. [24] | Shannon index | Greater diversity in psoriasis | PCA | Significant difference |
| Tan et al. [25] | Shannon index, Simpson index, ACE index, Chao1 index |
No differences were observed | PCA, UPGMA |
Significant difference |
| Scher et al. [28] | Shannon index, Faith’s phylogenetic diversity index | Lower diversity in psoriasis | unweighted Unifrac analysis | Significant difference |
ACE—abundance-based coverage estimator; OTUs—operational taxonomic units; PCA—principal component analysis; UPGMA—The Unweighted Pair Group Method with Arithmetic Mean.