Table 1.
Liver enzyme abnormalities in COVID-19 disease vary and reflect the degree of inflammatory response, direct biliary injury by the virus, the presence or absence of ischemia/microthromboses, and possible drug-induced liver injury. Hypoalbuminaemia and high transaminases levels are associated with poor prognosis.
Albumin | Transaminases | GGT | Bilirubin | Alkaline Phosphatase | ||
---|---|---|---|---|---|---|
COVID-19 | Severe liver injury from inflammatory response (cytokine storm) |
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Variable |
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Variable |
Drug induced liver injury | Variable |
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Variable | Variable | Variable | |
Direct biliary injury | Variable | Variable |
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|
Ischemia/microthrombosis |
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Variable |
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Variable |