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. 2020 Jun 18;9(6):480. doi: 10.3390/pathogens9060480

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Phylogenetic analysis of amino acid sequences of the angiotensin-converting enzyme 2 (ACE2) receptor in different animals and humans. The ACE2 orthologous amino acid sequences were downloaded from NCBI (https://www.ncbi.nlm.nih.gov/gene/59272/ortholog/?scope=33554) and aligned with COBALT (https://www.ncbi.nlm.nih.gov/tools/cobalt/re_cobalt.cgi). The tree was generated using a maximum likelihood estimate with FastTree, under a JTT model. The graphic representation was made with the ggtree package in R, and each color in the multiple sequence aligment (msa) corresponds to an amino acid.