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. 2019 Nov 12;41(5):551–560. doi: 10.1093/carcin/bgz142

Figure 2.

Figure 2.

Bry promotes breast cancer cell invasion, migration, adhesion and colonization in the bone microenvironment. (A) The protein levels of Bry in Bry-knockdown cells or Bry-overexpression breast cancer cells compared with their respective control cells. (B) The chemotactic capacity of breast cancer cells toward osteoblast-like MG-63 cells was assessed using Transwell assays. (C) Assays to assess the adhesion capacity of breast cancer cells to osteoblast-like MG-63 cells. (D) Assays to assess the adhesion capacity of breast cancer cells to bone matrix. (E) The colonization ability of breast cancer cells in MG-63 CM was assessed using colony formation assays (*P < 0.05, **P < 0.01, ***P < 0.001).