Table 1.
CAST Study Outcome Measures Summary
| Outcome | Measure | Group* | Timepoint | Method of Analysis |
|---|---|---|---|---|
| Mental functioning | Mental Component Score of VR-12 (MCS) [51, 55] | PT, CG | T1, T2, and T3 |
-Descriptive analyses -T1-T2 (Treatment Effect): ANCOVA, complete case and multiple imputation analyses, subgroup analyses, quantile regression -T2-T3 (Sustainability): ANCOVA, complete case and multiple imputation analyses, subgroup analyses |
| Physical functioning | Physical Component Score (PCS) of VR-12 [51, 55] | PT, CG | T1, T2, and T3 |
-Descriptive analyses -T1-T2 (Treatment Effect): ANCOVA, complete case and multiple imputation analyses, subgroup analyses, quantile regression -T2-T3 (Sustainability): ANCOVA, complete case and multiple imputation analyses, subgroup analyses |
| Depressive symptoms | CESD-10 [56] | PT, CG | T1, T2, and T3 |
-Descriptive analyses -T1-T2 (Treatment Effect): ANCOVA, complete case and multiple imputation analyses, quantile regression -T2-T3 (Sustainability): ANCOVA, complete case and multiple imputation analyses |
| Anxiety symptoms | Generalized Anxiety Disorder scale (GAD-7) [57] | PT, CG | T1, T2, and T3 |
-Descriptive analyses -T1-T2 (Treatment Effect): ANCOVA, complete case and multiple imputation analyses, quantile regression -T2-T3 (Sustainability): ANCOVA, complete case and multiple imputation analyses |
| Perceived social support | Personal Resource Questionnaire (PRQ-2000) [58] | PT | T1, T2, and T3 |
-Descriptive analyses -T1-T2 (Treatment Effect): ANCOVA, complete case and multiple imputation analyses, quantile regression -T2-T3 (Sustainability): ANCOVA, complete case and multiple imputation analyses |
| Communication between patients and providers | Patient-Provider Communication questionnaire [59] | PT, CG | T1 and T2 |
-Descriptive analyses -T1: z test of proportions for group comparison, complete case analysis -T2: z test of proportions for group comparison, complete case analysis |
| Client-centredness of care | Adapted Client-Centred Care Questionnaire (CCCQ) [60] | PT, CG | T1, T2, and T3 |
-Descriptive analyses -T1: z test of proportions for group comparison, complete case analysis -T2: z test of proportions for group comparison, complete case analysis |
| Care experience | Integrated Care Patient-Reported Experience Measures (IC-PREMs) [61] | PT, CG | T1, and T2 |
-Descriptive analyses -T1: z test of proportions for group comparison, complete case analysis -T2: z test of proportions for group comparison, complete case analysis |
| Unmet care needs | Unmet Care Needs questionnaire | PT, CG | T1, T2, and T3 |
-Descriptive analyses - T1: z test of proportions for group comparison, complete case analysis -T2: z test of proportions for group comparison, complete case analysis |
| Caregiver strain | Modified Caregiver Strain Index (CSI) [62] | CG | T1, T2, and T3 |
-Descriptive analyses -T1-T2 (Treatment Effect): ANCOVA, complete case analysis -T2-T3 (Sustainability): ANCOVA, complete case analysis |
| Utilization of health and social services and associated costs | Institute for Clinical Evaluative Sciences (IC/ES), Health and Social Services Utilization Inventory (HSSUI) [63, 64] | PT, CG | T1, T2, and T3 |
-Descriptive analyses -T1-T2 (Treatment Effect): Mann-Whitney U test, complete case analysis, Hazard Ratio (95% CI) & Risk Difference (95% CI) for 30, 90 &180-day ED visits and hospital admissions -T2-T3 (Sustainability): Mann-Whitney U test, complete case analysis |
*PT = patient; CG = caregiver, *T1 = baseline; T2 = 6-month; T3 = 12 months