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. 2020 Jul 10;8:105. doi: 10.1186/s40478-020-00984-9

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Representative histopathology of CNS-HGNT BCOR tumors. a Solid, highly cellular, monomorphic growth pattern with rich, thin-walled capillary network. b Pleomorphic cells of astroglial-like appearance. c Oligodendroglial-like monomorphic cells with round nuclei surrounded by clear cytoplasm accompanied by chicken-wire pattern of vessels. d Infiltration of uniform neoplastic cells with round nuclei and microcalcifications. e Densely-packed, small, hyperchromatic cells and thin-walled capillary blood vessels. f, g Network of capillary blood vessels with chicken-wire appearance. h Perivascular ependymoma-like pseudorosette. i Small vessels surrounded by perivascular eosinophilic zones. j Hyalinized vessels or k thin-walled, round vessels in the spongy matrix. l Area composed of stellate cells within myxoid background. The scale bars: a, b, d-e, h, i – 50 μm; f – 40 μm; c, g-l – 30 μm