Table 1.
Demographics and characteristics of the patients. Tx: transplantation, CRF: Chronic renal failure, HT: Hypertension, RA: Romatoid arthritis, CRP: C reactive protein.
| Sex/age | Type of DM,year of diagnosis | HbA1c(%-mmol/mol) | CRP | Osteomyelitis | Vasculopathy | Neuropathy | Response toantibacterial therapy | Surgery,type of surgery | Bacteriologyof ulcer | Mycologyof ulcer | Result of the treatment | |
| 1 | F/79 | Type 2,10 | 6.1–43 | 13.69 | Yes | Yes | Yes | No | Yes, below-knee amputation | Hafnia alvei | Candida lipolytica | Despite fluconazole therapy, rapidly progressed to amputation |
| 2 | F/53 | Type 2,11 | 13.4–123 | 23.97 | Yes | No | Yes | Yes, partially | Yes,transmetatarsal amputation | Pseudomonas aeruginosa, | C. glabrata | Despite amphotericin Btherapy, rapidly progressed to amputation |
| 3 | M/63 | Type 2,10 | 13.3–122 | 26.2 | Yes | Yes | No | No | Yes, above-knee amputation | P. aeruginosa,Corynebacterium striatum | C. albicans | Amputation performedwithout further culture |
| 4 | M/49 | Type 2,1 | 13.0–119 | 11.96 | Yes | Yes | Yes | No | Yes,toe amputation | P. aeruginosa | C. albicans | Amputation performed without further culture |
| 5 | M/64 | Type 2,16 | No | 9,36 | Yes | Yes | Yes | Yes, partially | Yes,Ray’s amputation | - | C. albicans | Amputation performed without further culture |
| 6 | M/61 | Type 2,12 | No | 21.43 | Yes | Yes | No | No | Yes,transmetatarsal amputation | P. aeruginosa | Fusarium spp. | Amputation performed without further culture |
| 7 | M/68 | Type 2,19 | 6.2–44 | 9.16 | Yes | No | Yes | Yes, partially | Yes,transmetatarsal amputation | - | C. parapsilosis | Patient died before culture results |
| 8 | F/50 | Type 2,8 | 12.0–108 | 19.23 | Yes | Yes | No | No | No | Streptococcus agalactiae | C. glabrata | After amphotericin B therapyCaspofungin, Healed |
| 9 | M/63 | Type 2,3 | 7.3–56 | 23.30 | No | Yes | Yes | Yes, partially | Yes, Ray’s amputation | Klebsiella oxytoca, Enterobacter cloacae | C. krusei | Amputation performed without further culture |
| 10 | M/53 | Type 2,23 | No | 32.86 | yes | Yes | Yes | Yes, partially | No | Pseudomonas aeruginosa,Acinetobacter baumannii | C. glabrata | Patient died before culture results |
| 11 | M/54 | Type 2,15 | 9.0–75 | 1.0 | No | Yes | Yes | Yes, partially | Yes, only debridment | Staphylococcus aureus | C.albicans | After fluconazole therapy,Healed |
| 12 | M/68 | Type 2,10 | 7.9–63 | 16.63 | Yes | Yes | Yes | Yes, partially | Yes, toe amputation | Staphylococcus aureus, Providencia stuartii | Trichosporon asahii,Fusarium solani | After itraconazole therapy,Healed |
| 13 | M/56 | Type 2,20 | 6.2–44 | 4.7 | Yes | Yes | Yes | No | No | Alcaligenes faecalis, Proteus vulgaris | Fusarium spp. | After liposomal amphoterisin B, Healed |