Table 5. Differences in adverse events (AEs) between consolidation chemotherapy (CCT) and neoadjuvant chemoradiotherapy (nCRT).
| nCRT (n = 61) | CCT (n = 83) | |||
|---|---|---|---|---|
| Grade 1–2 | Grade 3–4 | Grade 1–2 | Grade 3–4 | |
| Any toxicities | 57 93.4% | 1 1.6% | 79 95.1% | 2 2.4% |
| Nausea | 6 | 0 | 14 | 0 |
| Fatigue | 4 | 0 | 0 | 0 |
| Diarrhea | 5 | 0 | 21 | 0 |
| Anal pain | 4 | 0 | 17 | 1 |
| Peripheral neuropathy | 0 | 0 | 2 | 0 |
| Anorexia | 7 | 0 | 5 | 0 |
| Abdominal pain | 5 | 0 | 9 | 0 |
| Constipation | 2 | 0 | 3 | 0 |
| Urinary tract infection | 1 | 0 | 1 | 0 |
| Myalgia | 1 | 0 | 1 | 0 |
| Sepsis | 0 | 0 | 0 | 0 |
| Leukopenia | 8 | 1 | 26 | 2 |
| Hand foot syndrome | 0 | 0 | 2 | 0 |
| Neutropenia | 6 | 0 | 10 | 0 |
| Anemia | 2 | 0 | 3 | 0 |
| Thrombocytopenia | 3 | 0 | 0 | 0 |
| Hyponatremia | 0 | 0 | 1 | 0 |