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. 2020 Jul 10;9(7):giaa076. doi: 10.1093/gigascience/giaa076

Table 2:

Mean PR-AUC over 16 cancers for recovering methylation-driving genes according to the imputed relative to the actual gene expression data

Missing rate SVD TOBMI Lasso TDimpute-self TDimpute
10% 0.972 0.971 0.965 0.980 0.983
30% 0.867 0.867 0.842 0.908 0.927
50% 0.737 0.703 0.702 0.807 0.848
70% 0.587 0.521 0.565 0.678 0.749
90% 0.391 0.308 0.390 0.397 0.601

Mean performance across 16 imputed cancer datasets is reported. TDimpute had the best results in all comparisons. All differences were statistically significant (pairedt-test, P-value < 0.05) between TDimpute and other methods.