Figure 3.

HF diet resulted in altered mRNA gene expression in transplanted kidneys at day 14 post-transplant. Inflammatory cytokine mRNA was upregulated in both WT (n=7) and WT+HF (n=9) allografts compared with isografts (n=5). Expression of the regulatory cytokine IL-10 was significantly increased and expression of proinflammatory cytokine IL-23 was decreased in WT+HF compared with WT allografts. Data are shown as the mean±SEM. Statistical analysis by ANOVA with Tukey post hoc analysis. ***P<0.001.