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. 2020 Jul 10;128(7):077004. doi: 10.1289/EHP6785

Table 7.

Individual constant elimination rate (yearly) and half-life (year) in the 17 airport employees for long-chain PFAS.

Subject Sample counts PFOA PFHxS PFHpS L-PFOS 1m-PFOS 3/4/5m-PFOS 2/6m-PFOS
Elimination ratea HLa p-Valuea Elimination rate HL p-Value Elimination rate HL p-Value Elimination rate HL p-Value Elimination rate HL p-Value Elimination rate HL p-Value Elimination rate HL p-Value
1 5 0.3 2.4 0.17 0.2 3.5 0.19 0.5 1.3 0.31 0.2 NA 0.30 0.3 2.0 0.10 0.4 1.9 0.13 0.2 NA 0.76
2 5 0.2 2.9 0.27 0.3 2.0 0.09 0.2 3.4 0.64 0.4 1.7 0.07 0.1 5.4 0.83 0.3 2.1 0.11 0.5 1.3 0.20
3 5 0.6 1.2 0.04 0.5 1.5 0.09 0.2 3.0 0.34 0.5 1.3 0.21 0.8 0.9 0.09 0.4 1.7 0.15 0.7 1.0 0.12
4 5 0.3 2.3 0.15 0.1 9.6 0.75 0.001 526 1.00 0.3 NA 0.24 0.1 NA 0.78 0.1 11 0.87 0.0 51 0.97
5 5 0.3 2.2 0.15 0.1 4.7 0.20 0.3 NA 0.19 0.6 1.2 0.13 0.1 5.9 0.75 0.2 3.1 0.16 0.4 1.6 0.56
6 4 0.2 2.9 0.39 0.1 NAb 0.42 0.1 6.1 0.43 0.04 17 0.87 0.1 NA 0.51 0.04 19 0.49 0.4 1.7 0.04
7 5 0.4 1.6 0.03 0.3 2.3 0.02 0.04 NA 0.88 0.006 108 0.92 0.3 NA 0.03 0.1 4.8 0.02 1.1 0.6 0.29
8 5 0.007 100 0.98 0.01 NA 0.94 0.6 NA 0.42 0.4 1.6 0.23 0.5 NA 0.13 0.2 NA 0.24 0.2 NA 0.44
9 5 0.4 1.9 0.05 0.04 NA 0.81 0.05 15 0.69 0.4 1.8 0.21 0.3 NA 0.10 0.1 10 0.70 0.2 4.2 0.50
10 5 0.3 2.1 0.25 0.4 1.9 0.11 0.4 1.8 0.46 0.2 NA 0.32 0.6 1.2 0.10 0.2 4.0 0.52 0.007 NA 0.97
11 5 0.5 1.5 0.12 0.2 3.0 0.39 1.7 0.4 0.20 0.1 4.7 0.56 1.9 0.4 0.15 2.0 0.4 0.15 1.7 0.4 0.10
12 5 0.7 1.0 0.00 0.4 1.6 0.04 0.6 1.1 0.08 0.8 0.9 0.01 0.03 26 0.95 0.5 1.3 0.09 1.7 0.4 0.03
13 5 0.4 1.6 0.02 0.5 1.4 0.01 0.2 NA 0.70 0.2 3.7 0.34 1.1 0.6 0.08 0.5 1.5 0.04 1.0 0.7 0.20
14 4 0.4 1.6 0.40 0.6 1.2 0.31 1.0 0.7 0.21 0.3 2.0 0.67 1.7 0.4 0.08 0.3 2.0 0.55 1.5 0.5 0.44
15 5 0.6 1.1 0.04 0.3 2.2 0.06 1.6 0.4 0.09 0.5 1.3 0.01 1.3 0.6 0.18 2.2 0.3 0.08 1.2 0.6 0.18
16 5 0.3 2.7 0.19 0.04 19 0.89 0.1 12 0.61 0.6 1.2 0.05 0.3 NA 0.02 0.3 2.0 0.12 0.1 NA 0.81
17 5 0.6 1.2 0.09 0.4 1.6 0.07 1.7 0.4 0.13 0.3 2.1 0.19 2.2 0.3 0.12 1.9 0.4 0.13 1.9 0.4 0.10

Note: HL, half-life; L-PFOS, linear perfluorooctane sulfonic acid; PFAS, perfluoroalkyl substances; PFHpS, perfluoroheptane sulfonic acid; PFHxS, perfluorohexane sulfonic acid; PFOA, perfluorooctanoic acid; 1m-PFOS, branched, perfluoro-1-methylheptanesulfonate; 2/6m-PFOS, branched, sum of perfluoro-2/6-methylheptanesulfonate; 3/4/5m-PFOS, branched, sum of perfluoro-3/4/5-methylheptanesulfonate.

a

The elimination rate and p-value were obtained from linear regression. Serum PFAS levels were log-transformed. The elimination rate denotes the negative value of the slope (β) from the model, and half-life is calculated as ln2/k.

b

Not applicable because the elimination rate was negative, indicating PFAS levels did not decrease during the 5-month follow-up.