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. Author manuscript; available in PMC: 2020 Jul 28.
Published in final edited form as: Cold Spring Harb Symp Quant Biol. 2020 Jan 3;84:95–104. doi: 10.1101/sqb.2019.84.039206

Figure 5. TIS granules are necessary for SET binding to CD47.

Figure 5.

(A) Wild-type TIS11B (TIS11B-WT) forms TIS granules, whereas mutant TIS11B (TIS11B-MUT) does not. (B) Presence of TIS11B-WT substantially increases SET binding, but expression of TIS11B that is unable to form TIS granules (TIS11B-MUT) has a small effect. mC, mCherry. Shown as in Figure 4B. Adapted from Ma & Mayr, 2019.