Table 2.
Fifteen hub genes in blue module related with pathological grade glioma
| Gene symbol | Gene Module Membership | Gene Trait Significance | PPI Connectivity Degree | Up/down |
|---|---|---|---|---|
| ANXA1 | 0.827343404 | 0.561923969 | / | Up |
| ANXA2 | 0.875803843 | 0.548157845 | / | Up |
| CLIC1 | 0.888418433 | 0.566527724 | / | Up |
| COL4A1 | 0.866139195 | 0.54930032 | 25 | Up |
| COL4A2 | 0.804525568 | 0.52982224 | 17 | Up |
| COL5A2 | 0.852490117 | 0.623360253 | 15 | Up |
| FAM46A | 0.875552138 | 0.546436775 | / | Up |
| IKBIP | 0.887210744 | 0.516772095 | / | Up |
| KCNB1 | 0.886305109 | 0.572156038 | / | Down |
| LAMB1 | 0.895113867 | 0.57687226 | 19 | Up |
| LAMC1 | 0.925793134 | 0.618090561 | 17 | Up |
| SEC24D | 0.888379385 | 0.567315315 | / | Up |
| SPPL2A | 0.873493419 | 0.536895048 | / | Up |
| TIMP1 | 0.852549775 | 0.547783447 | 27 | Up |
| VEGFA | 0.82564312 | 0.559968118 | 43 | Up |
Note: “/” means that the connection degree of this gene in PPI network is < 15 or the gene is not projected into PPI network.