Table 3. Sensitivity and sub-group random effects meta-analyses of tuberculosis and risk of cardiovascular disease and related mortality.
Sensitivity / Sub-Group Meta-Analysis | Pooled RR | 95% CI | 95% PI | p-value |
---|---|---|---|---|
Removed studies requiring a medical condition other than TB for inclusion from per-protocol meta-analysis | 1.77 | 1.12–2.7800 | 0.31–10.17 | 0.0140 |
Removed non-RF-adjusted estimates from per-protocol meta-analysis | 2.78 | 2.12–3.63 | 1.46–5.29 | <0.0001 |
Removed extra-pulmonary TB estimate from per-protocol meta-analysis. | 2.22 | 1.66–2.95 | 0.93–5.24 | <0.001 |
Sub-group: cardiovascular death only | 1.70 | 1.09–2.67 | .034–8.66 | 0.0205 |
Sub-group: cardiovascular events only | 1.44 | 0.87–2.40 | 0.0036–584.38 | 0.1557 |
CI = confidence interval, PI = prediction interval, RF = risk factor, RR = risk ratio, TB = tuberculosis.