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. 2020 Jul 10;15(7):e0235821. doi: 10.1371/journal.pone.0235821

Table 3. Sensitivity and sub-group random effects meta-analyses of tuberculosis and risk of cardiovascular disease and related mortality.

Sensitivity / Sub-Group Meta-Analysis Pooled RR 95% CI 95% PI p-value
Removed studies requiring a medical condition other than TB for inclusion from per-protocol meta-analysis 1.77 1.12–2.7800 0.31–10.17 0.0140
Removed non-RF-adjusted estimates from per-protocol meta-analysis 2.78 2.12–3.63 1.46–5.29 <0.0001
Removed extra-pulmonary TB estimate from per-protocol meta-analysis. 2.22 1.66–2.95 0.93–5.24 <0.001
Sub-group: cardiovascular death only 1.70 1.09–2.67 .034–8.66 0.0205
Sub-group: cardiovascular events only 1.44 0.87–2.40 0.0036–584.38 0.1557

CI = confidence interval, PI = prediction interval, RF = risk factor, RR = risk ratio, TB = tuberculosis.