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. 2020 Jun 29;14(6):e0008407. doi: 10.1371/journal.pntd.0008407

Table 4. Mean renal index scores and sample sizes (n) by antibody titer group for initially clinical (CLINICAL), initially subclinical (SUB), stranded (STRAND) and wild-caught (WILD) animals.

Titer group “0” contains all seronegative animals, titer group 0* contains only non-shedding (i.e. urine PCR negative) seronegative animals. P-values are for two-sided bootstrap Kolmogorov-Smirnov (KS) test comparisons between animal groups of renal index distributions for a given titer. P-values for WILD 11+ v. WILD are for one-sided bootstrap KS test comparisons within the WILD dataset, with the null hypothesis that the renal index distribution for the 11+ titer group will be greater. P-values for STRAND 0* v. STRAND are for two-sided bootstrap KS test comparisons within the STRAND dataset comparing renal index distributions of seronegative, non-shedding animals with the other titer groups.

    Antibody Titer Group
  11+ 9–10 6–8 1–5 0 0*
Mean (n) WILD 0.65 (8) -0.18 (8) -0.33 (11) -0.27 (22) -0.32 (683) -0.28 (562)
SUB - -0.49 (1) -0.11 (1) -0.42 (27) - -
CLINICAL 6.6 (18) 1.47 (26) 0.57 (22) - - -
STRAND 6.44 (181) 3.66 (76) 0.82 (22) 1.56 (45) 0.3 (473) 0.83 (78)
KS test p-value CLINICAL v. WILD 0.001 0.005 0.002 - - -
SUB v. WILD - - - 0.07 - -
STRAND v. WILD <0.001 <0.001 0.04 <0.001 <0.001 <0.001
STRAND v. CLINICAL 0.56 0.002 0.04 - - -
STRAND v. SUB - - - <0.001 - -
WILD 11+ v. WILD   0.11 0.04 0.02 0.04 -
STRAND 0* v. STRAND <0.001 <0.001 0.66 0.39 - -
WILD 0* v. WILD 0.07 0.38 0.66 0.06 - -