Table 2.
Demographic, clinical and laboratory findings from the patients at the time of computed tomography pulmonary angiography (CTPA) study.
| Presence of pulmonary thromboembolic disease |
Unadjusted p-value |
||
|---|---|---|---|
| Yes | No | ||
| Number of patients | 41 | 52 | |
| Parameter | |||
| Age, median (IQR) | 62 (56–69) | 57 (50.5–68.5) | 0.044 |
| Gender, n | 41 | 52 | 0.499 |
| Female | 13 | 20 | |
| Male | 28 | 32 | |
| Current smoker, n | 5 | 8 | 0.660 |
| Comorbidity, n | |||
| Hypertension | 20 | 24 | |
| Diabetes mellitus | 14 | 24 | |
| Chronic obstructive lung disease | 2 | 4 | |
| Malignancy | 6 | 4 | |
| Chronic kidney disease | 6 | 4 | |
| Coronary heart disease | 2 | 7 | |
| Asthma | 2 | 9 | |
| Obesity (BMI >30) | 13 | 18 | |
| None of the above | 7 | 9 | |
| Referral source, n (%) | |||
| Emergency department | 12 (29.3%) | 12 (23.0%) | |
| Intensive care unit | 13 (31.7%) | 7 (13.5%) | |
| Inpatient ward | 16 (39.0%) | 33 (63.5%) | |
| COVID-19 symptomatic disease duration prior to CTPA, days (IQR) | 16 (9–23) | 13 (7–17.25) | 0.246 |
| Wells scores, n | 0.801 | ||
| <4 points | 20 | 24 | |
| >4 points | 21 | 28 | |
| Laboratory findings, median (IQR) | |||
| White blood cell count (×109/l) | 10.36 (8.53–13.98) | 7.81 (5.64–10.76) | 0.058 |
| <4, n (%) | 0 (0%) | 4 (7.7%) | |
| 4–10, n (%) | 19 (46.3%) | 31 (59.6%) | |
| >10, n (%) | 22 (53.7%) | 17 (32.7%) | |
| Lymphocyte count (×109/l) | 1.11 (0.73–1.55) | 1.07 (0.74–1.59) | 0.670 |
| <0.8, n (%) | 13 (31.7%) | 17 (32.7%) | |
| Neutrophils count (×109/l) | 8.52 (6.48–11.61) | 6.07 (4.31–9.67) | 0.043 |
| Haemoglobin, g/l | 111 (84–126) | 121 (102–134.5) | 0.071 |
| Platelet count, ×109/l | 340 (245–412) | 289 (206–421) | 0.521 |
| Albumin, g/l | 27 (24–33) | 33 (29.5–37) | 0.001 |
| ALT, U/l | 44 (32–62.5) | 45 (27.5–80.5) | 0.222 |
| Creatinine, μmol/l | 82 (69–142) | 73 (59.5–126) | 0.557 |
| Urea | 9.2 (4.8–14.1) | 6.7 (4.2–9.15) | 0.018 |
| C-reactive protein | 146 (92–216.3) | 73 (59.5–126) | 0.068 |
| LDH, μ/l | 466 (389–600.75) | 561.5 (439.75–709.25) | 0.221 |
| Troponin I | 37 (19.5–99) | 17 (8–34) | 0.759 |
| D-dimer | 7465 (3835–8000) | 2450 (1170–3985) | 0.001 |
| Serum ferritin, μg/l | 837.5 (616.25–1371.5) | 1051.5 (678.25–2396.5) | 0.138 |
| Outcomes, n (%) | |||
| Death | 6 (14.6%) | 5 (9.6%) | 0.457 |
p-Values were using Student's t-test, chi-squared, and Mann–Whitney U-test respectively.
IQR, interquartile range; BMI, body mass index; ALT, alanine transaminase; LDH, lactate dehydrogenase.