Table 1.
Demographic characteristics of the cohort
| Total (n=380) | Moderate disease (n=149) | Severe disease (n=145) | Critical disease (n=86) |
p value |
|||||
|---|---|---|---|---|---|---|---|---|---|
| Overall | Moderate vs severe | Moderate vs critical | Severe vs critical | ||||||
| Age, years | 64·0 (53·0–73·0) | 56·0 (41·5–67·5) | 67·0 (58·0–76·0) | 68·0 (61·0–78·0) | <0·0001 | <0·0001 | <0·0001 | 1·0 | |
| Sex | |||||||||
| Female | 174 (46%) | 80 (54%) | 69 (48%) | 25 (29%) | 0·0011* | 0·89 | <0·0001 | 0·017 | |
| Male | 206 (54%) | 69 (46%) | 76 (52%) | 61 (71%) | .. | .. | .. | .. | |
| Comorbidity | |||||||||
| Any | 182 (48%) | 60 (40%) | 74 (51%) | 48 (56%) | 0·045* | 0·19 | 0·064 | 1·0 | |
| Diabetes | 61 (16%) | 14 (9%) | 30 (21%) | 17 (20%) | 0·017* | 0·020 | 0·071 | 1·0 | |
| Hypertension | 114 (30%) | 37 (25%) | 49 (34%) | 28 (33%) | 0·21* | .. | .. | .. | |
| Coronary heart disease | 22 (6%) | 11 (7%) | 3 (2%) | 8 (9%) | 0·030† | 0·097 | 1·0 | 0·064 | |
| Carcinoma | 20 (5%) | 4 (3%) | 8 (6%) | 8 (9%) | 0·085† | .. | .. | .. | |
| Other | 77 (20%) | 21 (14%) | 24 (17%) | 32 (37%) | <0·0001* | 1·0 | 0·00013 | 0·0012 | |
| Death | 55 (14%) | 0 | 2 (1%) | 53 (62%) | <0·0001† | 0·73 | <0·0001 | <0·0001 | |
Data are median (IQR) or n (%). For variables with overall p values graeter than 0·05, we did not perform group comparisons. Categorical variables were analysed using
*
χ2 test or
†
Fisher's exact test.