Table 2.
The effects of His on the levels of FBS, insulin, HOMA-IR, lipid profile & CRRs (TG, Chol, LDL, VLDL, HDL-C, CRR 1 and 2) and renal functional markers (UA & Cr) in control, UTD, and HTD groups
| Parameter | Control | UTD | HTD |
|---|---|---|---|
| FBS (mg/dl) | 104.83 ± 5.99 | 288.00 ± 29.01* | 225.28 ± 4.15*# |
| Insulin (μg/L) | 1.75 ± 0.04 | 1.43 ± 0.04* | 1.58 ± 0.03*# |
| HOMA-IR | 0.44 ± 0.02 | 1.06 ± 0.03* | 0.86 ± 0.06*# |
| Chol (mg/dl) | 65.46 ± 1.55 | 89.92 ± 4.47* | 73.50 ± 3.94# |
| TG(mg/dl) | 61.20 ± 2.9 | 101.45 ± 5.01* | 64.80 ± 3.95# |
| HDL - C (mg/dl) | 46.83 ± 0.6 | 23.36 ± 0.54* | 32.87 ± 0.85*# |
| LDL (mg/dl) | 6.39 ± 1.76 | 46.27 ± 4.38* | 27.66 ± 3.39*# |
| VLDL (mg/dl) | 12.24 ± 0.58 | 20.29 ± 1.00* | 12.96 ± 0.79# |
| CRR1 (TC/HDL-C) | 1.39 ± 0.03 | 3.86 ± 0.20* | 2.24 ± 0.14*# |
| CRR2 (LDL/HDL-C) | 0.13 ± 0.03 | 1.99 ± 0.19* | 0.85 ± 0.11*# |
| UA (mg/dl) | 1.41 ± 0.27 | 2.49 ± 0.31* | 1.25 ± 0.09# |
| Cr (mg/dl) | 0.60 ± 0.02 | 0.75 ± 0.03* | 0.62 ± 0.02# |
* Shows significant difference against the control group; # Shows significant difference against the UTD group
FBS: Fasting Blood Sugar, HOMA-IR: Homeostatic Model Assessment for Insulin Resistance, Chol: Cholesterol, TG: Triglyceride, HDL-C: High Density Lipoprotein Cholesterol, LDL: Low Density Lipoprotein, VLDL: Very Low Density Lipoprotein, CRR 1: Cardiac Risk Ratio 1, CRR 2: Cardiac Risk Ratio 2, UA: Uric Acid, Cr: Creatinine, UTD: Untreated Diabetic, HTD: His-Treated Diabetic