Table 2.
Evaluation of skin wound healing changes and area measurement of spleen in negative (healthy) control group (NC), positive control group 1 (PC-1), positive control group 2 (PC-2), treatment group 1 (MA, meglumine antimoniate), treatment group 2 (CS/PEO), treatment group 3 (CS/PEO/BBR), treatment group 4 (BBR). Values are expressed as mean±SD
| Groups |
Area measurement (mm
2
)
|
|
|---|---|---|
| Skin wound healing changes | Spleen | |
| NC | - | 129.937±26.746* |
| PC-1 | 53±17.568 | 204.80±26.345 |
| PC-2 | 55.750±20.105 | 180.20±37.738 |
| MA | -22.495±4.176* | 151.80±34.50* |
| CS/PEO | 2.540±0.751* | 260.20±39.129* |
| CS/PEO/BBR | -26.450±6.534* | 150.093±27.813* |
| BBR | -4.70±1.444* | 134.625±19.11* |
* Significant difference with PC-1 (one-way ANOVA)