Table 3.

Evaluation of parasite burden and mice weight changes in negative (healthy) control group (NC), positive control group 1 (PC-1), positive control group 2 (PC-2), treatment group 1 (MA, meglumine antimoniate), treatment group 2 (CS/PEO), treatment group 3 (CS/PEO/BBR), treatment group 4 (BBR). Values are expressed as mean±SD

Groups	Parasite burden		Mice weight changes (%)
	Wound	Spleen
	Score	Leishman body unit
NC	-	-	10.96 ±0.57
PC-1	6+	491±45.68	-2.27±0.25
PC-2	6+	505±48.566	-0.74±0.14*
MA	0	122±30.077*	-0.74±0.124*
CS/PEO	4+	459±45.04	5.18±0.866*
CS/PEO/BBR	1+	395±51.91*	11.93±0.947*
BBR	3+	433±41.88	1.32±0.26*

* Significant difference with PC-1 (one-way ANOVA)