Table 3. Clustered summary of in vivo infections.
Comparison of the sporozoite infectivity to mice of the different lines by adding the data from Table 2 where the respective controls were 100% infective. Data for wild type controls, MIC2-I domain and RevCharge parasites are from infections with hemolymph and salivary glands sporozoites as well as by bite experiments. All others summarize infections with hemolymph sporozoites only, as these parasites did not colonize the salivary glands efficiently.
| Parasite lines | Infected mice* |
|---|---|
| wild type controls | 24/24 |
|
MIC2-I domain
RevCharge |
20/20 11/17 |
| αX-I domain | 9/16 |
|
αL-I domain
trap∆I trap(-) |
1/14 0/8† 0/6 |
* Infected mice/inoculated (exposed) mice.
† Four additional mice injected with 5000 salivary gland sporozoites also remained uninfected.