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Curcumin induced apoptosis in HCC cells. SMMC-7721 (A, B) and Huh-7 (C, D) cells were incubated with 16μM Curcumin for 48 hours, and the apoptotic cells were examined by Annexin V-FITC and PI double staining. (A, C), The results of one such assay; and (B, D), mean ± SD of three independent experiments. *P < 0.05, ***P < 0.001, compared with DMSO.
