TABLE 10.
Area under curve in five trials of randomly splitting training (70%) and trial data (30%).
Entorhinal cortex volume |
Entorhinal cortex volume and texture |
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Trial |
Training cohort |
Validation cohort |
Training cohort |
Validation cohort |
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ROC analysis AUC | (95% CI) | P-value | ROC analysis AUC | (95% CI) | P-value | ROC analysis AUC | (95% CI) | P-value | ROC analysis AUC | (95% CI) | P-value | |
1 | 0.760 | 0.690–0.830 | 0.000 | 0.700 | 0.583–0.814 | 0.000 | 0.795 | 0.728–0.862 | 0.000 | 0.780 | 0.662–0.898 | 0.000 |
2 | 0.673 | 0.595–0.751 | 0.001 | 0.688 | 0.573–0.804 | 0.005 | 0.725 | 0.649–0.801 | 0.000 | 0.780 | 0.674–0.886 | 0.001 |
3 | 0.663 | 0.580–0.746 | 0.04 | 0.658 | 0.538–0.778 | 0.005 | 0.745 | 0.770–0.820 | 0.000 | 0.790 | 0.680–0.903 | 0.001 |
4 | 0.662 | 0.582–0.742 | 0.000 | 0.635 | 0.500–0.772 | 0.005 | 0.786 | 0.712–0.860 | 0.000 | 0.735 | 0.621–0.848 | 0.001 |
5 | 0.647 | 0.565–0.730 | 0.001 | 0.709 | 0.591–0.827 | 0.003 | 0.751 | 0.675–0.827 | 0.000 | 0.735 | 0.627–0.843 | 0.001 |
ROC, receiver operating characteristic; AUC, area under curve, CI, confidence interval.