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. 2020 Jul 2;11:888. doi: 10.3389/fphar.2020.00888

Table 3.

Comparision of percent of subjects achieving the pre-defined busulfan exposure (AUC) for the 1st PK assessment.

Number (%) of subjects within 80–120% of the predefined 1st dose AUC target Number (%) of subjects with <80% of the predefined 1st dose AUC target Number (%) of subjects with >120% of the predefined 1st dose AUC target
Cohort A
(N = 53) 		13 (25%) 40 (75%) 0 (0%)
Cohort B
(N = 74) 		37 (50%) 32 (43%) 5 (7%)
Cohort C
(N = 57) 		43 (75%) 9 (16%) 5 (9%)

Data expressed as number of subjects (%).