Table 4.

Comparison of the percent of subjects achieving the targeted cumulative busulfan exposure (cAUC) for three different dosing cohorts.

	Number (%) of subjects within 80–120% of the predefined cAUC target	Number (%) of subjects with <80% of the predefined cAUC target	Number (%) of subjects with >120% of the predefined cAUC target
Cohort A (N = 53)	35 (66%)	3 (6%)	15 (28%)
Cohort B (N = 76)	67 (88%)	3 (4%)	6 (8%)
Cohort C (N = 59)	59 (100%)	0 (0%)	0 (0%)

Data expressed as Data expressed as number of subjects (%).