Table 1.
Natural components that potentially inhibit SARS-CoV CPE.
| Components | Categories | EC50 (μg/ml) | CC50 (μg/ml) | SI | References |
|---|---|---|---|---|---|
| Lycorine | Alkaloids | (4.51 ± 0.34) × 10−3 | 4.3077 ± 0.2621 | >900 | Li et al., 2005b |
| APA | Agglutinins | 0.45 ± 0.08 | >100 | >222.2 | Keyaerts et al., 2007 |
| UDA | Agglutinins | 1.3 ± 0.1 | >100 | >78.8 | Keyaerts et al., 2007 |
| Morniga M II | Agglutinins | 1.6 ± 0.5 | >100 | >62.5 | Keyaerts et al., 2007 |
| Nictaba | Agglutinins | 1.7 ± 0.3 | >100 | >58.8 | Keyaerts et al., 2007 |
| EHA | Agglutinins | 1.8 ± 0.3 | >100 | >55.5 | Keyaerts et al., 2007 |
| Reserpine | Alkaloids | 2.07 | 15.22 | 7.3 | Wu, 2004 |
| LOA | Agglutinins | 2.2 ± 1.3 | >100 | >45.5 | Keyaerts et al., 2007 |
| IRA | Agglutinins | 2.2 ± 0.9 | 50 | 22.7 | Keyaerts et al., 2007 |
| HHA | Agglutinins | 3.2 ± 2.8 | >100 | >31.3 | Keyaerts et al., 2007 |
| IRA r | Agglutinins | 3.4 ± 2.0 | 55 | 16.2 | Keyaerts et al., 2007 |
| IRA b | Agglutinins | 4.4 ± 3.1 | 36 | 8.2 | Keyaerts et al., 2007 |
| CA | Agglutinins | 4.9 ± 0.8 | >100 | >20 | Keyaerts et al., 2007 |
| NPA | Agglutinins | 5.7 ± 4.4 | >100 | >17.5 | Keyaerts et al., 2007 |
| GNA | Agglutinins | 6.2 ± 0.6 | >100 | >16.1 | Keyaerts et al., 2007 |
| Escin (Aescin) | Saponins | 6.79 | 16.9 | 2.5 | Wu, 2004 |
| Cladistris | Agglutinins | 7.4 ± 0.2 | >100 | >13.5 | Keyaerts et al., 2007 |
| Baicalin | Flavonoids | 12.5 | >100 | >8 | Chen et al., 2004 |
| PMRIP m | Agglutinins | 18 ± 13 | >100 | >5.5 | Keyaerts et al., 2007 |
| AUA | Agglutinins | 18 ± 4 | >100 | >5.5 | Keyaerts et al., 2007 |
| TL M I | Agglutinins | 22 ± 6 | >50 | >2.3 | Keyaerts et al., 2007 |
| ML III | Agglutinins | 28 ± 11 | >100 | >12.6 | Keyaerts et al., 2007 |
| TL C II | Agglutinins | 38 ± 0 | >50 | >1.3 | Keyaerts et al., 2007 |
| LRA | Agglutinins | 48 | >100 | >2.1 | Keyaerts et al., 2007 |
| Morniga G II | Agglutinins | 50 ± 13 | >100 | >2 | Keyaerts et al., 2007 |
| Glycyrrhizin | Saponins | 300 ± 51 | >20000 | >67 | Cinatl et al., 2003 |