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. 2020 Jul 10;35(4):410–417. doi: 10.1007/s12291-020-00909-2

KEY CONCEPT 3: Obesity and COVID-19 pathogenesis

Intracellular invasion of SARS CoV2 is via ACE 2 receptors located on cells. Expression of these are upregulated in obese individuals, leading to increased susceptibility of obese patients to infection.