. Author manuscript; available in PMC: 2020 Sep 11.

Published in final edited form as: Pediatr Res. 2020 Jan 11;88(3):459–465. doi: 10.1038/s41390-020-0756-2

Table 3.

Major circulating biomarker findings. Baseline refers to pre-discharge DXA; Completion, at the end of study (approximately 12 months post discharge; C, active control group; and E, assisted exercise group. “Osteo” refers to osteocalcin.

		Female		Male
		Baseline	Completion	Baseline	Completion
IGF-1^* (ng/ml)	C	46.1±5.2	95.6±7.6	51.6±16.7	61.7±7.0
IGF-1^* (ng/ml)	E	56.0±6.0	73.2±8.1	52.6±6.3	70.3±7.2
IL-6 (pg/ml)	C	2.6±1.2	1.3±0.3	1.5±0.3	2.4±0.9
IL-6 (pg/ml)	E	3.8±1.8	2.4±0.9	1.8±0.6	2.1±1.0
IL-1ra^* (pg/ml)	C	8200±1643	1112±107	6042±1408	1959±593
IL-1ra^* (pg/ml)	E	5132±1148	1588±414	4275±1061	1365±150
Osteo^* (ng/ml)	C	90.2±10.0	59.3±5.7	74.1±9.1	43.1±6.0
Osteo^* (ng/ml)	E	96.5±12.8	52.1±3.5	90.6±13.9	55.0±5.8

significant change between baseline and completion (across condition and sex) p < 0.0125