Table 3.
Differences in the Alterations of dFC of the S1 Cortex Between the LBLP and HCs Groups (Two-Sample t-Test, Two-Tailed, Voxel-Level P < 0.01, GRF Correction, Cluster-Level P < 0.05)
| Brain Regions | BA | Peak T-Scores |
MNI Coordinates | Cluster Size (Voxels) | zFC-values*(LBLP vs HCs) | Effect Size (Cohen’s d) |
||
|---|---|---|---|---|---|---|---|---|
| x | y | z | ||||||
| dFC of the right S1hand (LBLP vs HCs) | ||||||||
| Left precentral and postcentral gyrus (PRG/POG) | 3,4 | 3.271 | −24 | −48 | 57 | 75 | 0.003 ± 0.001 vs −0.001 ± 0.007 | 1.004 |
| dFC of the right S1finger (LBLP vs HCs) | ||||||||
| Right PRG/POG | 3, 4, 6 | 4.207 | 57 | −18 | 36 | 129 | 0.004 ± 0.001 vs −0.001 ± 0.007 | 1.413 |
Note: *mean±standard error.
Abbreviations: LBLP, low-back-related leg pain; HCs, healthy controls; dFC, dynamic functional connectivity; S1hand, representation of the hand in the primary somatosensory cortex; BA, Brodmann’s area; MNI, Montreal Neurological Institute Coordinate System.