Table 1.
Protein Families and Groups with Differing Expression Levels between Capillary and Schirmer Strip Samples
Higher Expression in | Family/Group | No. of Proteins | Proteins |
---|---|---|---|
Capillary samples | Immunoglobulin heavy/light/J chain | 46 | a |
Keratin, type I | 7 | KRT10, KRT12, KRT14, KRT16, KRT17, KRT36, KRT9 | |
Keratin, type II | 6 | KRT1, KRT2, KRT6B, KRT78, KRT82, KRT86 | |
Cysteine protease family C1 related | 3 | CTSC, CTSS, CTSZ | |
Secretoglobin | 3 | SCGB2A1, SCGB2A2, SCGB1D1 | |
Complement component | 3 | C1R, C1S, C2 | |
Schirmer strip samples | Heat-shock protein | 7 | HSP90AA1, HSP90AB1, HSPA1B, HSPA4, HSPA8, HSPB1, HSPD1 |
Annexin | 6 | ANXA1, ANXA11, ANXA2, ANXA3, ANXA4, ANXA5 | |
Chaperonin (T-complex proteins) | 6 | CCT2, CCT3, CCT5, CCT6A, CCT8, TCP1 | |
S100 calcium-binding protein | 6 | S100A11, S100A4, S100A6, S100A8, S100A9, S100P | |
Proteasome subunit α/β | 5 | PSMA3, PSMA4, PSMA6, PSMB1, PSMB10 | |
Thioredoxin peroxidase | 4 | PRDX1, PRDX2, PRDX5, PRDX6 | |
Serpin | 4 | SERPINA1, SERPINA7, SERPINB1, SERPINB5 | |
Tubulin | 4 | TUBA1B, TUBA4A, TUBB, TUBB4B | |
ARP2/3 complex 16-kD subunit | 4 | ARPC3, ARPC5, ARPC4, ARPC5L | |
Ras-related protein Rab | 4 | RAB10, RAB1B, RAB27B, RAB5B | |
Superoxide dismutase [Cu-Zn] | 3 | SOD1, SOD2, SOD3 | |
Actin or actin related | 3 | ACTG1, ACTR2, ACTR3 | |
14-3-3 protein | 3 | SFN, YWHAG, YWHAZ | |
Immunoglobulin heavy chain | 3 | IGHG1, IGHG2, IGHG4 | |
Aldehyde dehydrogenase related | 3 | ALDH1A1, ALDH3A1, ALDH9A1 | |
Fetuin | 3 | AHSG, FETUB, KNG1 |
Protein names omitted due to large number of proteins and missing protein abbreviations.