Table 4.
Levels of leukocytes and neutrophils count, and inflammation-associated biomarkers in confirmed COVID-19 patient with underlying chronic disease at admission
| Normal range | All patients (n = 52) |
Patients with underlying chronic disease (n = 37) | Patients without underlying chronic disease (n = 15) | P value | |
|---|---|---|---|---|---|
| Leukocytes, × 109 per L | 3.5–9.5 | 11.96 (11.39–13.15) | 12.30 (11.79–14.73) | 11.40 (11.22–12.54) | 0.007 |
| ≥ 12, n (%) | 25 (48.1) | 20 (54.1) | 5 (33.3) | 0.175 | |
| < 12, n (%) | 27 (51.9) | 17 (45.9) | 10 (66.7) | ||
| Neutrophils, × 109 per L | 1.8–6.3 | 10.58 (9.58–12.22) | 10.86 (9.92–13.31) | 9.99 (8.51–10.67) | 0.012 |
| Increased, n (%) | 50 (96.2) | 37 (100) | 13 (86.7) | 0.079 | |
| Decreased, n (%) | 0 | 0(0) | 0(0) | ||
| Procalcitonin, ng/mL | < 0.1 | 0.21 (0.06–0.64) | 0.23 (0.06–0.74) | 0.08 (0.06–0.59) | 0.613 |
| Increased, n (%) | 31 (59.6) | 24 (64.9) | 7 (46.7) | 0.226 | |
| C-reactive protein, mg/L | 0–10 | 78.7 (46.3–153.3) | 91.4 (50.6–186.7) | 45.1 (6.8–107.7) | 0.010 |
| Increased, n (%) | 44 (84.6) | 35 (94.6) | 9(60.0) | 0.005 | |
| Interleukin-6, pg/mL | ≤ 20.0 | 22.15 (11.94–67.79) | 35.40 (15.94–83.00) | 14.27 (8.00–28.41) | 0.005 |
| Increased, n (%) | 27 (51.9) | 23 (62.2) | 4 (26.7) | 0.02 |
Data are median (IQR) or n (%). Increased means over the upper limit of the normal range and decreased means below the lower limit of the normal range. COVID-19 coronavirus disease 2019