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. 2020 Jul 10;39(12):2279–2287. doi: 10.1007/s10096-020-03976-8

Table 5.

Complications and clinical outcomes at data cutoff in patients with COVID-19

Complications n (%) All patients (n = 619) Patients with increased leukocytes (n = 52) Patients with non-increase leukocytes (n = 567) P value
Any 137 (22.1) 38 (73.1) 99 (17.5) < 0.001
Acute renal injury 28 (4.5) 9 (17.3) 19 (3.4) < 0.001
Acute respiratory distress syndrome 83 (13.4) 24 (46.2) 59 (10.4) < 00.01
Septic shock 16 (2.6) 5 (9.6) 11(1.9) 0.007
Secondary infection 46 (7.4) 11 (21.2) 35 (6.2) 0.001
  Other viruses 6 (1.0) 1 (1.9) 5 (0.9)
  Bacteria 35 (5.7) 7 (13.5) 28 (1.9)
  Fungus 5 (1.0) 2 (3.8) 3 (0.5)
Clinical outcomes, n (%)
Incidence of SIRS 134 (21.6) 35 (67.3) 99 (17.5) < 0.001
Incidence of critically illness 100 (16.1) 26 (50.0) 74 (13.1) < 0.001
Admission to ICU 91 (14.7) 24 (46.2) 67 (11.8) < 0.001
Discharge from hospital 451 (72.9) 32 (61.5) 419 (73.9) 0.055
Death 43 (6.9) 10 (19.2) 33 (5.8) 0.002
Hospitalization 125 (20.2) 10 (19.2) 115 (20.3) 0.857

COVID-19 coronavirus disease 2019, ICU intensive care unit, SIRS systemic inflammatory response syndrome