Table 2.
Laboratory findings of patients with COVID-19.
| Laboratory Findings |
Median (IQR) |
P Valuea |
|||
|---|---|---|---|---|---|
| Blood routine (white blood cells) | Normal range | Total (n = 334) | Hospitalized (n = 212) | Discharged (n = 122) | |
| White blood cells (× 109/L) | 3.5–9.5 | 5.40(4.53, 6.69) | 5.44(4.68, 6.69) | 5.20(4.33, 6.62) | 0.1072 |
| Neutrophils (× 109/L) | 1.8–6.3 | 3.40(2.27, 4.30) | 3.45(2.81, 4.35) | 3.14(2.40, 4.04) | 0.0142 |
| Neutrophil percentage % | 40–75 | 61.67(56.18, 66.75) | 62.49(57.63, 67.32) | 59.10(53.68, 66.53) | 0.0033 |
| Lymphocytes (× 109/L) | 1.1–3.2 | 1.38(1.08, 1.71) | 1.37(1.04, 1.63) | 1.43(1.20, 1.77) | 0.0454 |
| Lymphocytes percentage | 20–50 | 26.2(20.9, 31.55) | 25.3(20, 30.15) | 28.43(23.38, 33.13) | 0.0006 |
| Monocytes (× 109/L) | 0.1–0.6 | 0.47(0.38, 0.59) | 0.49(0.41, 0.61) | 0.43(0.36, 0.56) | 0.0050 |
| Monocyte percentage % | 3–10 | 8.85(7.27, 10.68) | 9.05(7.42, 10.73) | 8.565(7.23, 10.58) | 0.3076 |
| Eosinophils (× 109/L) | 0.02–0.52 | 0.09(0.05, 0.17) | 0.10(0.06, 0.17) | 0.09(0.05, 0.13) | 0.0063 |
| Eosinophil percentage % | 0.4–8.0 | 1.64(0.95, 2.77) | 1.79(1.03, 2.98) | 1.5(0.91, 2.48) | 0.1032 |
| Basophils (× 109/L) | <0.06 | 0.02(0.01, 0.03) | 0.02(0.02, 0.03) | 0.02(0.01, 0.03) | 0.1250 |
| Basophil percentage % | 0–1 | 0.38(0.29, 0.51) | 0.39(0.31, 0.52) | 0.36(0.26, 0.48) | 0.9043 |
| Lymphocyte Subsets | Normal range | Total (n = 303) | Hospitalized (n = 190)1 | Discharged (n = 113)1 | |
| B cells (CD3−CD19+) (×107/L) | 4.1–18.31 | 12.01(7.89, 16.80) | 11.30(7.31, 16.41) | 17.52(12.46, 18.76) | 0.0398 |
| NK cells (CD3−CD16+CD56+) (×107/L) | 3.33–30.47 | 8.26(4.99, 12.82) | 9.33(6.46, 12.98) | 3.53(2.84, 6.27) | 0.0027 |
| CD 3+ T cells (CD3+CD19−) (×107/L) | 58–17-84.22 | 76.41(68.91, 81.04) | 76.32(68.90, 81.17) | 76.43(69.23, 80.89) | 0.9882 |
| CD8+ T cells (CD3+CD8+) (×107/L) | 14.32–38.95 | 21.64(16.97, 28.05) | 20.67(15.99, 27.21) | 23.57(18.32, 29.41) | 0.0079 |
| CD4+ T cells (CD3+CD4+) (×107/L) | 25.34–51.37 | 47.69(42.70, 53.88) | 48.99(42.66, 55.68) | 47.08(42.82, 51.58) | 0.0396 |
| CD4+ /CD8+ | 0.41–2.72 | 2.01(1.56, 2.93) | 2.25(1.59, 3.06) | 1.90(1.53, 2.66) | 0.0297 |
| Inflammatory cytokines | Normal range | Total (n = 312) | Hospitalized (n = 212) | Discharged (n = 100) | |
| Tumor necrosis factor-α (pg/mL) | 0.1–23 | 3.18(2.25, 5.14) | 3.60(2.50, 5.39) | 2.57(2.12, 4.31) | 0.0011 |
| Interleukin-2 (pg/mL) | 0.1–4.1 | 2.56(2.31, 2.88) | 2.60(2.34, 3.02) | 2.47(2.22, 2.70) | 0.0007 |
| Interleukin-4 (pg/mL) | 0.1–3.2 | 2.11(1.58, 2.63) | 2.26(1.66, 2.80) | 1.91(1.53, 2.32) | 0.0013 |
| Interleukin-6 (pg/mL) | 0.1–2.9 | 14.70(5.29, 54.88) | 18.29(6.23, 57.32) | 9.18(4.07, 50.03) | 0.0057 |
| Interleukin-10 (pg/mL) | 0.1–5 | 3.18(2.59, 4.10) | 3.37(2.73, 4.50) | 2.82(2.37, 3.36) | <0.0001 |
| Interferon-γ (pg/mL) | 0.1–18 | 2.03(1.60, 2.58) | 2.13(1.71, 2.79) | 1.84(1.44, 2.23) | 0.0006 |
a
P values indicate differences between the hospitalized and the discharged patients. P < .05 was considered statistically significant. Means for continuous variables were compared using independent group t-test when the data were normally distributed; otherwise, the Mann-Whitney test was used. 1. The tests of B and NK cells were only performed for 34 inpatients and 7 discharged patients.