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. 2020 May 26;16(8):448–466. doi: 10.1038/s41574-020-0357-5

Table 2.

Summary of studies evaluating pectin, guar gum and glucomannan in dumping syndrome

Study n Treatment Result
Jenkins et al.104 9 Pectin 14.5 g, single administration prior to OGTT Improved symptoms and glycaemia levels (normalized in 46%) during OGTT
Jenkins et al.105 11 Pectin 14.5 g, single administration prior to OGTT Improved postprandial levels of glucose, insulin and enteroglucagon; reduced hypoglycaemia
Leeds et al.153 11 Pectin 15 g, single administration prior to OGTT Improved vasomotor symptoms and glycaemia levels, lower insulin levels and slower gastric emptying during OGTT
Lawaetz et al.44 4 Pectin 15 g, single administration prior to OGTT Reduced vasomotor symptoms, lower levels of insulin, glucagon, neurotensin and gastric inhibitory polypeptide, and slower initial gastric emptying during OGTT
Andersen et al.100 5 Pectin 5 g, single administration prior to muffin meal No effect on symptoms or gastric emptying rate
Harju and Larmi101 11 Guar gum 5 g with meals Improvement of symptoms
Harju et al.102 11 Guar gum 5 g with meals Slowing of gastric emptying
Harju and Makela103 11 Guar gum 5 g with a glucose challenge meal Improvement of symptoms and hyperglycaemia after a glucose challenge meal
Kneepkens et al.106 8 children Glucomannan 1.3 g, single administration prior to OGTT Improvement of glucose tolerance, no effect on glucose absorption; however, no consistent effect on symptoms was seen

OGTT, modified oral glucose tolerance test.