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. 2020 Jul 10;3:370. doi: 10.1038/s42003-020-1093-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — Longitudinal changes in ALS participants (n = 11), in FA, RD, MD, and AD (averaged across C2–C6) in (a) whole spinal cord, (b) spinal white matter, (c) descending tracts, (d) lateral CST, (e) spinal lemniscus, and (f) posterior columns. The line between initial and one year data connects the means (the numerical values in the text). The box plots show the median (circle with dot), 25th and 75th percentiles (edges of the box), and the range of FA/CSA (the whisker end points) excluding the outliers (individual circles).