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. 2020 Jul 10;10:11469. doi: 10.1038/s41598-020-68493-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Macular complications of cuticular drusen. (A) Geographic atrophy is seen on (A1) CFP, (A2) FAF, (A3) FA, and (A4) OCT in a 65-year-old man with cuticular drusen. Geographic atrophy appears in both eyes symmetrically. Large drusen are also visible on CFP and OCT. (B) Type 3 choroidal neovascularization is seen on (B1) CFP, (B2) FAF, (B3) FA, and (B4) OCT in a 67-year-old woman with cuticular drusen. (C) Drusenoid pigment epithelial detachment and acquired vitelliform lesion appear as (C1) round yellow lesions on CFP, (C2) intense hyperautofluorescence on FAF, (C3) hypofluorescence in the early phase of FA, and a (C4) subretinal location of vitelliform material with pigment epithelial detachment is seen on OCT, in a 74-year-old man. The position of the OCT line scans is shown in the CFP as a white transverse line. CFP color fundus photograph, FA fluorescein angiography, FAF fundus autofluorescence, OCT optical coherence tomography.