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. 2020 Jul 10;10:11469. doi: 10.1038/s41598-020-68493-2

Table 3.

Comparison of recent cuticular drusen studies.

Author(s), year No. of patients Sex (female:male) Mean
Age (years)
Region Imaging tools for diagnosis of CD GA (%) Neovascular AMD (%) AVL (%)
Cohen et al., 199414 19 13:6 61.4 France CFP, FAa 0 31.6c 100d,e
Barbazetto et al., 20076 28 17:11 65.9 United States CFP, AF, FAb 3.6d 3.6d 100d,e
Boon et al., 200810 30 20:10 53.3 Netherlands CFP, NIR, OCT, AF, FAa 33.3d 16.7d 26.7d
Boon et al., 201312 198 Netherlands CFP, RF, NIR, OCT, AF, FAa, ICGA 56d
Balaratnasingam et al., 20184 120 72:48 57.9 United States, Australia, France CFP, RF, NIR, OCT, AF, FAb, ICGA 25.0c 12.5c 24.2c
Sakurada et al., 201913 12 8:4 60.8 Japan CFP, NIR, OCT, AF, FAa, ICGA 8.3c 4.2c 0
Sakurada et al., 201919,f 38 35:3 59.9 United States CFP, FAF, OCT, FAa 14.5f 2.6f
Current study, 2018 81 67:14 66.6 Korea CFP, RF, NIR, OCT, AF, FAa, ICGA 18.5c 3.7c 1.2c

– unknown, AF fundus autofluorescence, AMD age-related macular degeneration, AVL acquired vitelliform lesion, CD cuticular drusen, CFP color fundus photography, FA fluorescein angiography, GA geographic atrophy, ICGA indocyanine green angiography, NIR near-infrared, OCT optical coherence tomography, RF red-free imaging.

aFA was performed in all patients.

bFA was performed in selected patients.

c% of eyes.

d% of patients.

ePatients who had both vitelliform or pseudovitelliform detachment and cuticular drusen were included.

fBaseline cross-sectional data before exclusion.