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GMDR analysis of rs694539 and rs1941404 NNMT, rs1421085 FTO, and rs3751723 IRX3 for obesity.
| Phenotypes | Model | Testing accuracy (%) | CVC | OR (95% CI) | p-value |
|---|---|---|---|---|---|
| Obese/non-obese | rs694539, rs1941404, rs1421085, rs3751723 | 0.674 | 5/5 | 4.62 (1.75–12.10) | 0.001 |
| Obese/non-obese | rs694539, rs1941404, rs1421085, rs3751723* | 0.744 | 5/5 | 9.86 (1.42–68.40) | < 0.05 |
* Predictors: gender, age, HDL-c, LDL-c, triglycerides, REE, acylated ghrelin, leptin, HOMA-IR.
