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. 2019 Jul 5;59(5):1845–1858. doi: 10.1007/s00394-019-02036-y

Table 2.

Energy, macronutrient and food group intake by dietary group

Dietary variable Control
Mean (95% CI)a,b (n = 47)
Strict Paleolithic
Mean (95% CI)b (n = 22)
Effect size (SP vs control) Pseudo-Paleolithic
Mean (95% CI)b (n = 22)
Effect size (PP vs control) Overall dietary effect P valuec
Energy intake (kJ) 9187 (8599, 9774) 8955 (8076, 9834) − 0.13 9820 (9005, 10635) 0.33 0.285
Protein (g) 92.16 (83.69, 100.63) 118.07 (105.69, 130.44)** 1.02 102.7 (90.62, 114.77) 0.39 0.001
Protein (% of energy) 18.49 (16.87, 20.12) 23.63 (21.25, 26.00)** 1.02 20.13 (17.81, 22.45) 0.39 0.001
Carbohydrate (g) 202.62 (187.84, 217.41) 99.19 (77.60, 120.79)** − 2.33 81.40 (60.34, 102.47)** − 2.59 < 0.001
Carbohydrate (% of energy) 38.03 (35.49, 40.57) 16.75 (13.03, 20.46)** − 2.79 16.41 (12.79, 20.03)** − 2.69 < 0.001
Sugars (g) 75.58 (66.05, 85.11) 51.77 (37.85, 65.68)** − 0.83 44.34 (30.76, 57.91)** − 1.04 < 0.001
Starch (g) 124.56 (112.87, 136.26) 45.86 (28.78, 62.95)** − 2.24 34.74 (18.07, 51.4)** − 2.43 < 0.001
Total fat (g) 82.53 (76.33, 88.72) 117.91 (108.86, 126.96)** 1.90 133.16 (124.34, 141.99)** Inline graphic 2.58 < 0.001
Fat (% of energy) 36.45 (33.9, 39) 52.95 (49.22, 56.67)** 2.15 56.96 (53.33, 60.6)** 2.54 < 0.001
Saturated fat (g) 27.34 (22.77, 31.9) 45.51 (38.84, 52.18)** 1.33 52.47 (45.97, 58.98)** 1.74 < 0.001
Saturated fat (% of energy) 12.02 (10.05, 13.99) 20.59 (17.71, 23.47)** 1.45 22.09 (19.28, 24.9)** 1.61 < 0.001
Polyunsaturated fat (g) 15.17 (13.21, 17.14) 16.86 (13.98, 19.73) 0.29 17.47 (14.67, 20.28) 0.37 0.295
Monounsaturated fat (g) 32.96 (29.63, 36.28) 45.01 (40.16, 49.86)** 1.21 52.28 (47.55, 57.02)** Inline graphic 1.84 < 0.001
Cholesterol (mg) 324.19 (225.29, 423.08) 708.28 (563.84, 852.73)** 1.29 685.00 (544.10, 825.90)** 1.15 < 0.001
Total dietary fiber (g) 29.66 (26.36, 32.96) 27.41 (22.59, 32.23) − 0.23 20.79 (16.09, 25.49)* − 0.85 0.006
Soluble dietary fiber (g) 11.99 (10.45, 13.53) 10.78 (8.54, 13.03) − 0.26 7.62 (5.43, 9.81)** Inline graphic − 0.90 0.004
Insoluble dietary fiber (g) 17.07 (15.11, 19.03) 16.17 (13.3, 19.04) − 0.15 12.87 (10.07, 15.66)* − 0.68 0.036
Resistant starch minimum (g) 4.48 (3.89, 5.06) 2.62 (1.77, 3.47)** − 1.03 1.26 (0.43, 2.09)** Inline graphic − 1.75 < 0.001
Resistant starch maximum (g) 14.16 (12.24, 16.07) 6.13 (3.34, 8.93)** − 1.35 2.95 (0.22, 5.68)** − 1.85 < 0.001
Alcohol (g) 7.07 (3.73, 10.4) 8.31 (3.44, 13.19) 0.12 10.34 (5.59, 15.09) 0.31 0.488
Vegetables serves/day (fresh equivalent 150–350 kJ) 3.83 (2.99, 4.66) 6.68 (5.51, 7.84)** 1.12 4.31 (3.17, 5.44) 0.16 < 0.001
Dark green vegetable serves/day (fresh equivalent 100 kJ) 0.39 (0.17, 0.61) 1.28 (0.97, 1.59)** 1.34 0.70 (0.41, 1.00) 0.45 < 0.001
Nuts and seeds (30 g protein equivalent) 0.82 (0.48, 1.15) 1.07 (0.59, 1.56) 0.26 1.32 (0.84, 1.79) 0.48 0.167
Red meat serves/day (20 g protein equivalent) 0.44 (0.21, 0.66) 0.80 (0.47, 1.13) 0.52 0.77 (0.45, 1.09) 0.46 0.066
Eggs serves/day (13 g protein equivalent) 0.20 (0.09, 0.30) 1.05 (0.72, 1.38)** 0.87 0.89 (0.57, 1.21)* 0.63 < 0.001
Total grains serves/day (14–16 g starch equivalent) 6.14 (5.29, 7.04) 0.19 (0.03, 0.47)** − 3.80 0.63 (0.30, 1.08)** − 3.07 < 0.001
Whole grain serves/day (14 g starch equivalent) 2.91 (2.28, 3.61) 0.09 (0.00, 0.34)** − 2.32 0.16 (0.01, 0.46)** − 2.09 < 0.001
Total dairy serves/day (300 mg calcium equivalent) 1.60 (1.25, 2.0) 0.17 (0.04, 0.37)* − 1.26 0.87 (0.54, 1.27)* Inline graphic − 0.73 < 0.001

P values for stratified Paleolithic groups were adjusted using post hoc Bonferroni correction [43]

Significant P values are in bold

aGeneral linear modelling used to determine estimated marginal means and the difference between control and the overall Paleolithic groups after adjustment for age, gender, energy intake and body fat percentage.**P ≤ 0.01 different from control group, *P ≤ 0.05 different to control group

bGeneral linear modelling used to determine estimated marginal means and the difference between control, strict Paleolithic and Pseudo-Paleolithic groups after adjustment for age, gender, energy intake and body fat percentage.**P ≤ 0.01 different from control group, *P ≤ 0.05 different to control group. Inline graphicP < 0.01 different from Strict Paleolithic group, Inline graphicP < 0.05 different from the SP group

cSignificance of the overall general linear model for the three group analysis. Effect sizes reported using Cohen’s d, with a value of 0.2 representing a small effect, 0.5 a medium effect and 0.8 a large effect