. 2020 Mar 26;36(3):203–210. doi: 10.1007/s43188-019-00013-5

Table 3.

The values of leukon parameters (mean ± SEM) of rats in dermal toxicity study of M. malabathricum leaf ethanolic extract

Parameter	G1	G2	G3	G4	G5
Acute toxicity study
WBC (× 10⁹/L)	6.58 ± 0.24^a	6.69 ± 0.44^a	6.80 ± 0.30^a	6.94 ± 0.51^a	6.84 ± 0.45^a
Neutrophils (× 10⁹/L)	1.27 ± 0.09^a	1.33 ± 0.07^a	1.23 ± 0.10^a	1.24 ± 0.12^a	1.27 ± 0.16^a
Lymphocytes (× 10⁹/L)	4.60 ± 0.20^a	4.63 ± 0.36^a	4.88 ± 0.22^a	4.93 ± 0.31^a	5.02 ± 0.38^a
Monocyctes (× 10⁹/L)	0.49 ± 0.03^a	0.46 ± 0.03^a	0.44 ± 0.03^a	0.42 ± 0.05^a	0.47 ± 0.07^a
Eosinophils (× 10⁹/L)	0.19 ± 0.04^a	0.15 ± 0.02^a	0.17 ± 0.07^a	0.14 ± 0.01^a	0.15 ± 0.02^a
Basophils (× 10⁹/L)	0.08 ± 0.03^a	0.08 ± 0.02^a	0.08 ± 0.02^a	0.06 ± 0.02^a	0.07 ± 0.02^a
Subacute toxicity study
WBC (× 10⁹/L)	6.51 ± 0.55^a	6.25 ± 0.17^a	6.60 ± 0.37^a	6.70 ± 0.92^a	6.87 ± 0.33^a
Neutrophils (× 10⁹/L)	1.22 ± 0.08^a	1.15 ± 0.08^a	1.22 ± 0.07^a	1.17 ± 0.09^a	1.09 ± 0.07^a
Lymphocytes (× 10⁹/L)	4.47 ± 0.46^a	4.40 ± 0.09^a	4.53 ± 0.31^a	4.70 ± 0.61^a	4.95 ± 0.11^a
Monocyctes (× 10⁹/L)	0.50 ± 0.04^a	0.44 ± 0.04^a	0.42 ± 0.04^a	0.43 ± 0.04^a	0.43 ± 0.05^a
Eosinophils (× 10⁹/L)	0.14 ± 0.04^a	0.20 ± 0.02^a	0.12 ± 0.02^a	0.14 ± 0.02^a	0.15 ± 0.01^a
Basophils (× 10⁹/L)	0.10 ± 0.01^a	0.10 ± 0.02^a	0.10 ± 0.02^a	0.07 ± 0.01^a	0.07 ± 0.00^a

Values in the same row with similar superscripts are not significantly different at p > 0.05

G1: M. malabathricum (2.5%), G2: M. malabathricum (5%), G3: M. malabathricum (10%), G4: negative control, G5: paraffin