Table 1.
Patient characteristics during ICU stay and mortality rate depending on coagulopathy scoring system
| All patients (n = 582) | Positive SIC score (n = 486/577) | Positive JAAM-DIC score (n = 193/561) | Positive ISTH overt-DIC score (n = 182/567) | |
|---|---|---|---|---|
| D7-mortality, n (%) | 115 (19.8) | 105 (21.6) | 60 (31.1) | 69 (37.9) |
| D28-mortality, n (%) | 207 (35.5) | 181 (37.2) | 95 (49.1) | 107 (58.7) |
| SOFA (mean ± SD) | 11.0 ± 3.2 | 11.2 ± 3.2 | 12.8 ± 2.9 | 12.8 ± 2.9 |
| SAPS II (mean ± SD) | 61.2 ± 19.3 | 64.1 ± 19.3 | 66.0 ± 19.2 | 67.8 ± 20.4 |
| Mechanical ventilation, n (%) | 518 (89.1) | 437 (90.0) | 180 (93.4) | 172 (94.7) |
| Vasopressor, n (%) | 582 (100) | 486 (100) | 193 (100) | 182 (100) |
| Dialysis, n (%) | 172 (29.5) | 155 (31.9) | 86 (44.5) | 93 (51.1) |
| Nosocomial infection, n (%) | 82 (14.1) | 70 (14.4) | 27 (14.0) | 23 (12.6) |
| Infection source, n (%) | ||||
| Pneumonia | 236 (40.5) | 191 (39.3) | 68 (35.2) | 66 (36.3) |
| Urinary tract infection | 102 (17.5) | 89 (18.3) | 43 (22.3) | 38 (20.9) |
| Abdominal infection | 89 (15.3) | 74 (15.2) | 36 (18.7) | 34 (18.7) |
| Catheter infection | 11 (1.9) | 9 (1.9) | 6 (3.1) | 5 (2.7) |
| Positive blood culturea | 136 (23.4) | 114 (23.5) | 53 (27.5) | 52 (28.6) |
| Other | 75 (12.9) | 65 (13.4) | 18 (9.3) | 18 (9.9) |
| Bacteria, n (%)b | ||||
| Staphylococcus | 99 (17.0) | 74 (15.2) | 33 (17.1) | 26 (14.3) |
| Pneumococcus | 41 (7.0) | 35 (7.2) | 15 (7.8) | 14 (7.7) |
| Other GPC | 68 (11.7) | 54 (11.1) | 21 (10.9) | 25 (13.7) |
| E. coli | 118 (20.3) | 105 (21.6) | 44 (22.8) | 46 (25.3) |
| KES | 90 (15.5) | 78 (16.0) | 28 (14.5) | 28 (15.3) |
| Pseudomonas | 33 (5.7) | 30 (6.2) | 12 (6.2) | 12 (6.6) |
| Other GNB | 84 (14.4) | 69 (14.2) | 27 (14.0) | 27 (14.8) |
| Other | 38 (6.5) | 36 (7.4) | 5 (2.6) | 8 (4.4) |
Scores were positive if ISTH overt-DIC score was ≥ 5 points, JAAM-DIC score was ≥ 4 points, and SIC was ≥ 4 points at day 1 or 2 after ICU admission for septic shock
GNB Gram-negative bacillus, GPC Gram-positive cocci, KES Klebsiella, Enterobacter, Serratia
aBacteriemia was isolated in 15 (2.6%) patients
bAt least one bacteria was identified in 406 (69.8%) patients