Table 1.
Characteristics of high-risk SCC patients subdivided by origin: CSCC vs. HNSCC. SCC: squamous cell carcinoma, CSCC: cutaneous squamous cell carcinoma, HNSCC: head and neck squamous cell carcinoma, SD: standard deviation, n.a.: not applicable.
| Characteristics | Total Population (n = 56) | CSCC (n = 37) | HNSCC (n = 19) |
|---|---|---|---|
| Age, mean (SD) | 70 (11) | 72 (10) | 67 (11) |
| Male gender, n (%) | 49 (87.5%) | 34 (91.9%) | 15 (78.9%) |
| Tumor differentiation, n (%) | |||
| Well differentiated | 4 (7.1%) | 3 (8.1%) | 1 (5.3%) |
| Moderately differentiated | 18 (32.1%) | 8 (21.6%) | 10 (52.6%) |
| Poorly differentiated | 10 (17.9%) | 8 (21.6%) | 2 (10.5%) |
| Missing | 24 (42.9%) | 18 (48.6%) | 6 (31.6%) |
| Primary tumor, n (%) | |||
| pT1 | 31 (55.3%) | 22 (59.5%) | 9 (47.4) |
| pT2 | 11 (19.6%) | 10 (27.0%) | 1 (5.3%) |
| pT3 | 4 (7.1%) | 2 (5.4%) | 2 (10.5%) |
| pT4 | 10 (17.9%) | 3 (8.1%) | 7 (36.8%) |
| Regional lymph nodes, n (%) | |||
| cN0, pN not assessed | 41 (73.2%) | 32 (86.5%) | 9 (47.4%) |
| pN0 | 8 (14.3%) | 1 (2.7%) | 7 (36.8%) |
| pN1 | 2 (3.6%) | 1 (2.7%) | 1 (5.3%) |
| pN2 | 5 (9.0%) | 3 (8.1%) | 2 (10.5%) |
| Surgical margin status, n (%) | |||
| R0 | 30 (53.6%) | 19 (51.4%) | 11 (57.9%) |
| Narrow | 12 (21.4%) | 7 (18.9%) | 5 (26.3%) |
| R1 | 14 (25.0%) | 11 (29.7%) | 3 (15.8%) |
| Immune Status, n (%) | |||
| Compromised | n.a. | 14 (37.8%) | n.a. |
| Potentially compromised | n.a. | 7 (18.9%) | n.a. |
| Not compromised | n.a. | 16 (43.2%) | n.a. |