Table 2.
Changed miRNAs and target genes by ingenuity pathway analysis (IPA).
| MicroRNAs | Log2(FC) | p Value | Putative Target Genes by IPA |
|---|---|---|---|
| hsa-miR-122-5p | 1.095 | <0.001 | AACS, ADAM17, AKT3, ALDOA, ANK2, ANXA11, AP3M2, ATP11A, ATP1A2, BACH2, BCKDK, BCL2L2, CCNG1, CD320, CERS6, CLDN18, CS, DSTYK, DUSP2, EGLN3, ENTPD4, FAM117B, FOXJ3, FOXP1, FUNDC2, G6PC3, GALNT10, GPX7, GYS1, HJV, MAPK11, MECP2, MEP1A, NCAM1, NDRG3, NFATC1, NFATC2IP, NUMBL, OSMR, PALM, RAB11FIP1, RAB6B, RABIF, SLC35A4, SLC7A1, SLC7A11, TBX19, TMED3, TMEM50B, TPD52L2, TRIB1, TRPV6, TTYH3, UBAP2, XPO6 |
| hsa-miR-429 | 1.145 | <0.001 | BAP1, ELMO2, ERBIN, ERRFI1, FHOD1, FOXF2, GEMIN2, GSE1, KLHL20, MARCKS, PLCG1, PPM1F, PTEN, PTPN12, PTPN13, PTPRD, RERE, WASF3, WDR37, ZEB1, ZEB2, ZFPM2 |
| hsa-miR-324-5p | 1.003 | <0.001 | GLI1, RUNX1, SMO, SRF |
| hsa-miR-378d | 0.933 | <0.001 | IGF1R, ODC1, SUFU, TUSC2 |
| hsa-miR-483-5p | 1.019 | <0.001 | ALCAM, ARHGDIA |
| hsa-miR-515-3p | 0.89 | <0.001 | BCL11B, BCOR, BTG1 |
| hsa-miR-519c-3p | 1.007 | <0.001 | ABCG2, AR, PRKAA1 |
| hsa-miR-144-3p | 1.359 | <0.001 | ENPP6 |
| hsa-miR-216a-5p | 0.996 | <0.001 | PTEN |
| hsa-miR-217 | 1.308 | <0.001 | TRPS1 |
| hsa-miR-495-3p | 0.891 | <0.001 | ONECUT1 |
| hsa-miR-504-5p | 1.207 | <0.001 | VEGFA |
| hsa-miR-512-3p | 1.403 | <0.001 | CFLAR |
| hsa-let-7a-5p | −3.794 | <0.001 | AARSD1, ACP1, ADGRG1, AGO4, AKAP8, ANAPC1, ATAD3B, ATP6V0A1, ATP6V1F, AURKB, BCL2L1, BCL7A, BMP2K, BSG, CALCOCO2, CAPG, CARHSP1, CASP3, CCND1, CDC25A, CDIPT, CDK6, CDKAL1, CEMIP2, CHMP2A, CIAO2A, COIL, COL1A2, COMMD9, CSDE1, CSNK1D, DAD1, DHX57, DICER1, DOCK5, DRD3, DSP, DUSP12, DUSP23, EIF3J, EIF4G2, F2, FADS2, FANCD2, FNDC3A, GAK, GEMIN7, GRPEL2, GTPBP3, GYS1, HMGA1, HMGA2, Hmga2, HMOX1, HYOU1, IFIT5, IFRD1, IGF2BP1, IGF2BP2, IGF2BP3, IPO4, ITGB3, KCNJ16, KLK10, KRAS, KRT19, LIN28A, MARS2, MED28, MLLT1, MRM1, MRPS24, MRPS33, MTPN, MTRR, MYC, NEDD4, NF2, NRAS, NXN, OTULINL, PGRMC1, POLD2, POLR2C, POM121/POM121C, PPP1R7, PRDM1, PRIM1, PRRC2A, PTGS2, PXDN, RABGAP1L, RAS, RBM19, RDH10, RHOB, RHOG, RPP38, RRP8, RTCA, SCYL1, SEPT3, SIGMAR1, SLC1A4, SLC25A1, SLC25A13, SLC25A24, SLC25A32, SLC38A1, SMC1A, SMOX, SNAP23, SPCS3, SPRYD4, SYPL1, TAF9B, TAGLN, TGFBR1, THBS1, TLR4, TPM2, TRIM71, TRMT1, TTC9C, TUSC2, TYMS, UGT8, UHRF1, VIM, VPS39, WNT1 |