Table 3.
Macrovascular endothelial function in response to the 6-week low carbohydrate diet intervention.
| LC without CR Diet (n = 9) |
LC with CR Diet (n = 12) |
P Group × Time |
P Group |
P Time |
|||
|---|---|---|---|---|---|---|---|
| Brachial Artery | Baseline | Week 6 | Baseline | Week 6 | |||
| FMD, % | 6.5 ± 1.1 | 5.9 ± 1.5 | 7.8 ± 1.4 | 9.6 ± 1.6 | 0.4 | 0.1 | 0.7 |
| Baseline diameter, mm | 3.05 ± 0.17 | 3.15 ± 0.25 | 3.28 ± 0.15 | 3.24 ± 0.12 | 0.4 | 0.5 | 0.7 |
| Maximum diameter, mm | 3.26 ± 0.19 | 3.32 ± 0.24 | 3.52 ± 0.14 | 3.56 ± 0.14 | 0.8 | 0.3 | 0.4 |
| Peak flow, cm/s | 105 ± 12 | 120 ± 12 | 94 ± 10 | 106 ± 10 | 0.8 | 0.4 | 0.08 |
| Peak shear rate, | 334 ± 42 | 373 ± 40 | 269 ± 27 | 300 ± 29 | 0.9 | 0.1 | 0.2 |
| NTG-mediated dilation, % | 25.8 ± 3.8 | 24.7 ± 1.9 | 24.6 ± 2.5 | 28.5 ± 2.3 | 0.9 | 0.99 | 0.4 |
| Baseline diameter, mm | 3.01 ± 0.17 | 3.01 ± 0.20 | 3.34 ± 0.14 | 3.26 ± 0.14 | 0.6 | 0.2 | 0.6 |
| Maximum diameter, mm | 3.83 ± 0.21 | 3.76 ± 0.21 | 4.11 ± 0.13 | 4.16 ± 0.13 | 0.2 | 0.2 | 0.8 |
Data are mean ± SEM. CR = calories restriction; FMD = flow-mediated dilation; LC = low-carbohydrate; NTG = nitroglycerin.