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Hispolon, an AKT inhibitor (LY294002) (A) and an ER inhibitor (4-PBA) (B) regulated protein expression in LPS-challenged mice. Lung tissue extracts were subjected to Western blot analysis, using antibodies for iNOS, COX-2, Beclin-1, caspase 12 and CHOP. Data are represented as means ± S.E.M. (n = 3). ### p < 0.001, compared with the control group. ** p < 0.01 and *** p < 0.001 versus the LPS group.
