α -syn	α-synuclein
Aβ	β-amyloid
AD	Alzheimer’s disease
AIM2	absent in melanoma 2
ALS	amyotrophic lateral sclerosis
AMP	antimicrobial peptides
APCs	antigen-presenting cells
APOE	apolipoprotein E
ASC	apoptosis-associated speck-like protein containing a carboxy-terminal CARD
BMDCs	bone marrow-derived dendritic cells
CARD	caspase activation and recruitment domain
CD	Crohn’s disease
CIA	arthritis induced by collagen
CNS	central nervous system
DAMP	danger-associated molecular pattern
DCM	diabetic cardiomyopathy
DSS	dextran sodium sulfate
EAE	experimental autoimmune encephalomyelitis
FFAs	free fatty acids
HFD	high-fat diet
IAPP	islet amyloid polypeptide
IBDs	Inflammatory Bowel Diseases
IFN	interferon
IL	interleukin
IL-1R	IL-1 receptor
IL-1RA	IL-1R antagonist
IRF	interferon regulatory factor
IRS-1	insulin receptor substrate-1
LDL	low-density lipoprotein
LPS	lipopolysaccharide
LRR	leucine-rich repeat
MALT-1	mucosa-associated lymphoid tissue lymphoma translocation protein 1
MCP-1	monocyte chemoattractant protein-1
MI	myocardial infarction
MOG	myelin oligodendrocyte glycoprotein peptide
MPTP	1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
MS	multiple sclerosis
MyD88	myeloid differentiation primary response 88
NADPH	nicotinamide adenine dinucleotide phosphate
NF-kB	nuclear factor kappa-light-chain-enhancer of activated B cells
NLR	NOD-like receptors
NO	nitric oxide
NOD	nucleotide-binding oligomerization domain
Nrf2	NFE-related factor 2
oxLDL	oxidized low-density lipoprotein
PAMP	pathogen-associated molecular pattern
PBMCs	peripheral blood mononuclear cells
PD	Parkinson’s disease
PNS	peripheral nervous system
PYRIN	amino-terminal pyrin domain
PRR	pattern recognition receptor
RA	Rheumatoid Arthritis
RE	Rasmussen’s Encephalitis
ROS	reactive oxygen species
SIRT1	Sirtuin 1
T2D	type 2 diabetes
TAC	transverse aortic constriction
TLR	Toll-like receptor
TNBS	2,4,6-trinitrobenzenesulfonic acid
TNF	tumor necrosis factor
TXNIP	thioredoxin-interacting protein
UC	ulcerative colitis