ASC |
Apoptosis-associated speck-like protein containing a CARD |
BRET |
Bioluminescence resonance energy transfer |
CoIP |
Co-immunoprecipitation |
eATP |
Extracellular adenosine tri-phosphate |
ELISA |
Enzyme-linked immunosorbent assay |
FADD |
Fas-associated protein with Death Domain |
GSDMD |
Gasdermin D |
IL |
Interleukin |
iLPS |
Intracellular LPS |
iPS |
Induced pluripotent Stem cells |
KO |
Knock-out |
LDH |
Lactate dehydrogenase |
mROS |
Mitochondrial reactive oxygen species |
NFkB |
Nuclear factor kappa-light chain enhancer of activated B cells |
NLRP3 |
NLR family pyrin domain containing 3 |
PAMPI |
Pathogen-associated molecular pattern |
PTM |
Post-translational modifications |
RIPK |
Receptor-interacting seriine-threonine-protein kinase 1 |
SRP |
Surface plasmon resonance |
TLR |
Toll-like receptor |
TR-FRET |
Time-resolved fluorescence resonance energy transfer |
TRIF |
TIR domain-containing adapter inducing interferon-β |
Wt |
Wild-type |