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. 2020 Jun 17;21(12):4306. doi: 10.3390/ijms21124306
3NT 3-nitrotyrosine
4-HNE 4-hydroxynonenal
8-oxoG 8-hydroxyguanosine
amyloid beta peptide
ACE2 angiotensin-converting enzyme 2
BBB blood–brain barrier
CD68 cluster of differentiation 68—also macrosialin
CI confidence interval
CNS central nervous system
COVID-19 coronavirus disease 2019
COX-2 inducible cyclooxygenase (isoform 2)
DEP diesel exhaust particles
EC elemental or black carbon
γ-H2AX H2A histone family member X
GBD Global Burden of Disease
GEMM Global Exposure-Mortality Model
gp91phox catalytic subunit of the phagocytic NADPH oxidase (isoform 2)—also NOX-2
H3K9me2/me3 histone 3 lysine 9 di- and trimethylation (epigenetic marks)
HR hazard ratio
ICAM-1 intercellular adhesion molecule 1
INF-γ interferon gamma
IHME Institute for Health Metrics and Evaluation
IL-1β interleukin-1β
iNOS inducible nitric oxide synthase
IQR interquartile range
Ly6g lymphocyte antigen 6 complex locus G6D
MCP-1 monocyte chemoattractant protein-1—also CCL2
MyD88 myeloid differentiation primary response 88 protein
NFκB nuclear factor ‘kappa-light- chain-enhancer’ of activated B-cells
NOx oxides of nitrogen
NOX-2 catalytic subunit of the phagocytic NADPH oxidase (isoform 2)—also gp91phox
OC organic carbon
OR odds ratio
oxLDL oxidized low density lipoprotein
p47phox regulatory subunit of the phagocytic NADPH oxidase (isoform 2)
PAHs polycyclic aromatic hydrocarbons
PCBs polychlorinated biphenyls
PM0.1 particulate matter < 0.1 µm (ultrafine particles)
PM2.5 particulate matter < 2.5 µm (fine particles)
PM10 particulate matter with a diameter between 2.5 and 10 µm (coarse particles)
RANTES chemokine (C-C motif) ligand 5—also CCL5
ROS reactive oxygen species
RR relative risk
SARS-CoV-2 severe acute respiratory syndrome coronavirus 2
SNS sympathetic nervous system
TLR4 Toll-like receptor 4
TNFα tumor necrosis factor alpha
TNFR2 tumor necrosis factor receptor type 2
UK United Kingdom
US United States
VOCs volatile organic compounds
WHO World Health Organization